Cilostazol: What It Is and Why It Matters

If you’ve been told to take cilostazol, you probably have peripheral artery disease (PAD) or need help with blood flow in your legs. Cilostazol is a prescription medicine that works by widening blood vessels and stopping platelets from sticking together. The result? Better circulation and less pain when you walk.

Unlike some older PAD drugs, cilostazol also has a mild effect on how the body handles cholesterol, which can add a small extra benefit. It’s taken as a tablet, usually twice a day, and you’ll hear most doctors say you should keep it up for at least a month before judging how well it works.

Uses and Benefits

The main reason doctors prescribe cilostazol is to improve walking distance for people with PAD. Studies show that many patients can walk farther after a few weeks on the drug. It can also be used for intermittent claudication, the cramp‑like pain you feel when muscles don’t get enough blood.

Some doctors also use cilostazol off‑label for certain stroke prevention plans, but that’s less common and should only happen under close supervision.

Dosage & Safety Tips

The usual dose is 100 mg taken twice daily, at least 30 minutes before or two hours after a meal. If you miss a dose, take it as soon as you remember unless it’s almost time for the next one—don’t double up.

Because cilostazol can raise heart rate, it isn’t recommended for people with certain heart problems, uncontrolled high blood pressure, or severe liver disease. If you’re pregnant, nursing, or planning to become pregnant, talk to your doctor first; the drug isn’t usually advised in those cases.

Common side effects include headache, diarrhea, and a feeling of nausea. Most of these are mild and go away on their own. If you notice chest pain, sudden swelling of the feet, or an irregular heartbeat, stop the medication and call a health professional right away.

To get the most out of cilostazol, combine it with a healthy lifestyle. Regular walking, a balanced diet, and quitting smoking all boost circulation and help the medicine work better.

Lastly, keep an eye on any other meds you’re taking. Cilostazol can interact with certain blood thinners, some antibiotics, and drugs that affect liver enzymes. A quick check with your pharmacist can prevent unwanted surprises.

In short, cilostazol can be a solid tool for easing PAD symptoms when used correctly. Stick to the prescribed schedule, watch for side effects, and pair the drug with good habits for the best results.